We have been living in Cambodia for several years. The country does not require extraordinary medical preparation — but some basic rules apply. Consulting a doctor or an international vaccination center 6 to 8 weeks before departure remains the best decision you can make.
The information in this article is provided for informational purposes only. It does not replace the advice of a healthcare professional. Consult your doctor or an international vaccination center (IVC) before traveling to a tropical area.
Recommended vaccinations for Cambodia
No vaccination is mandatory to enter Cambodia if you are coming from France (unless you are coming from a country endemic to yellow fever). However, several vaccinations are strongly recommended by French health authorities.
Essential vaccinations
- Hepatitis A: transmitted through contaminated water and food. Real risk in Cambodia, including in tourist restaurants. Highly effective vaccine, 2 injections covering 20 years.
- Typhoid: same mode of transmission as hepatitis A. Vaccine recommended especially if you eat outside the usual tourist circuits (markets, street food).
- DTP (Diphtheria-Tetanus-Polio): check that your booster is up to date. Polio is officially eradicated in Cambodia, but DTP remains a basic requirement.
Vaccinations based on your travel profile
- Rabies: recommended if you plan to hike in rural areas, possible contact with animals (stray dogs, bats), or an extended stay. Rabies is present in Cambodia — and a bite without vaccination requires quickly finding immunoglobulins, which are not always available locally.
- Japanese encephalitis: recommended for prolonged stays in rural or rice-growing areas, especially during the rainy season. Not necessary for a typical tourist circuit.
- Hepatitis B: recommended if you expect to receive medical care on-site, engage in activities with a risk of injury, or have an extended stay.
Where to get vaccinated in France?
Consult an International Vaccination Center (IVC) — available in all major French cities. Your general practitioner can also prescribe and administer these vaccines. Ideally, make an appointment 6 to 8 weeks before departure to have time for necessary boosters.
Malaria — what is the real risk?
Malaria exists in Cambodia, but the risk is very low for tourist travelers visiting the typical areas: Phnom Penh, Siem Reap, Kampot, the beaches of Sihanoukville, and the islands are considered negligible risk areas.
The risk becomes more significant in forested and border areas, notably:
- Mondulkiri (forested province in the east)
- Ratanakiri (northeast border province)
- Cardamom forest areas
For a standard stay (Phnom Penh + Siem Reap + beaches), an anti-malarial treatment is generally not necessary. However, mosquito repellents and mosquito nets are sufficient as protection. If you are heading to Mondulkiri or Ratanakiri, consult your doctor — prophylactic treatment may be recommended.
Cambodia is also affected by resistance to classic anti-malarials (chloroquine, mefloquine). In case of prescription, atovaquone-proguanil (Malarone) is generally recommended by French doctors for this region.
Dengue and mosquito protection
Dengue is present in Cambodia year-round, peaking during the rainy season (June-October). Unlike malaria, it can affect urban areas — including Phnom Penh and Siem Reap.
There is no specific treatment for dengue (symptoms are treated). Prevention relies entirely on protection against mosquitoes:
- Body repellent: DEET 30-50% or IR3535, to be applied to exposed areas at dusk (but also during the day for dengue)
- Long clothing: especially in the evening, cover arms and legs
- Mosquito net: useful in budget guesthouses or rural areas
- Air conditioning: mosquitoes dislike cold — an air-conditioned room significantly reduces the risk
High sudden fever, intense muscle and joint pain, severe headaches, rash after 3-7 days: consult immediately. Do not take ibuprofen or aspirin if dengue is suspected — only paracetamol until you can see a doctor.
Water, sun, and heat
Tap water
Tap water is not drinkable in Cambodia. Even in good hotels, it is not intended for direct consumption. Drink exclusively:
- Bottled water (easily available everywhere, $0.25 to $0.50 / 1.5L)
- Filtered water (some hotels and cafes offer filters)
- Boiled water
Ice in tourist restaurants is generally made from filtered water and is safe. In more remote street stalls, it’s better to avoid or ask.
Sun and heat
Cambodia is close to the equator: the sun is intense year-round, and the heat can be exhausting, especially in March-April (35 to 40°C). A few precautions:
- High SPF sunscreen (SPF 50+): available at pharmacies in Cambodia, but cheaper if you bring it from France
- Hat and sunglasses
- Avoid full exposure between 11 AM and 3 PM for temple visits — go early in the morning
- Hydration: drink regularly, at least 2 to 3L of water per day in hot weather
Clinics and pharmacies in Phnom Penh
In case of health problems, Phnom Penh has several quality private clinics with English-speaking staff:
In Siem Reap, the Royal Angkor International Hospital also has a good technical platform and English-speaking doctors. For serious cases requiring complex surgery, transfer to Bangkok is sometimes arranged.
Pharmacies
Pharmacies are very numerous in Phnom Penh and Siem Reap. Many medications available only by prescription in France are sold without prescription in Cambodia — convenient in emergencies, but always consult a doctor for any serious issue. The quality of local generic medications varies: prefer licensed pharmacies and well-known brands.
Recommended travel pharmacy
Bringing a small first aid kit will save you from having to search for a pharmacy in an emergency for everyday minor injuries:
- Antiseptic: Betadine or Biseptine — cuts and scrapes in Cambodia can get infected quickly in warm and humid conditions
- Anti-diarrheal: Smecta or loperamide — traveler's diarrhea is common in the first few days
- Oral rehydration: rehydration salt packets (ORS) — essential in case of diarrhea due to high heat
- Antihistamine: for allergic reactions or insect bites
- Pain reliever / antipyretic: paracetamol only (no ibuprofen if dengue is suspected)
- Bandages and sterile compresses
- Mosquito repellent: DEET or IR3535 — cheaper to bring than to buy locally
Bring enough medication for the entire duration of the trip + one extra week (in case of delays or extensions). Keep them in your carry-on luggage with the corresponding prescription, especially if they are regulated substances.
Emergency numbers in Cambodia
In case of a serious medical emergency, first call your travel insurance — they can arrange a transfer to the most suitable clinic and direct care.